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Synovial fluid hyaluronan mediates MSC attachment to cartilage, a potential novel mechanism contributing to cartilage repair in osteoarthritis using knee joint distraction

OBJECTIVES: Knee joint distraction (KJD) is a novel, but poorly understood, treatment for osteoarthritis (OA) associated with remarkable ‘spontaneous’ cartilage repair in which resident synovial fluid (SF) multipotential mesenchymal stromal cells (MSCs) may play a role. We hypothesised that SF hyalu...

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Detalhes bibliográficos
Publicado no:Ann Rheum Dis
Main Authors: Baboolal, Thomas G, Mastbergen, Simon C, Jones, Elena, Calder, Stuart J, Lafeber, Floris P J G, McGonagle, Dennis
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4853581/
https://ncbi.nlm.nih.gov/pubmed/25948596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/annrheumdis-2014-206847
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