Overlap between differentially methylated DNA regions in blood B lymphocytes and genetic at-risk loci in primary Sjögren's syndrome

BACKGROUND: Beyond genetics, epigenetics alterations and especially those related to DNA methylation, play key roles in the pathogenesis of autoimmune diseases such as primary Sjögren's syndrome (pSS) and systemic lupus erythematosus. This study aimed to assess the role of methylation deregulat...

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Detalhes bibliográficos
Publicado no:Ann Rheum Dis
Main Authors: Miceli-Richard, Corinne, Wang-Renault, Shu-Fang, Boudaoud, Saida, Busato, Florence, Lallemand, Céline, Bethune, Kevin, Belkhir, Rakiba, Nocturne, Gaétane, Mariette, Xavier, Tost, Jörg
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2016
Assuntos:
Basic and Translational Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4853580/
https://ncbi.nlm.nih.gov/pubmed/26183421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/annrheumdis-2014-206998
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