Decreased miR-199 augments visceral pain in patients with IBS through translational upregulation of TRPV1

OBJECTIVE: Many patients with irritable bowel syndrome IBS not only have abdominal pain but also may suffer from visceral hypersensitivity and heighted visceral nociception. Moreover, IBS has few effective therapeutic agents and mechanisms of disease are unclear. Our goals were to (i) identify micro...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Gut
Autori principali: Zhou, QiQi, Yang, Liuqing, Larson, Scott, Basra, Sapreet, Merwat, Shehzad, Tan, Alai, Croce, Carlo, Verne, G Nicholas
Natura: Artigo
Lingua:Inglês
Pubblicazione: BMJ Publishing Group 2016
Soggetti:
Neurogastroenterology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4853572/
https://ncbi.nlm.nih.gov/pubmed/25681400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gutjnl-2013-306464
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