Decreased miR-199 augments visceral pain in patients with IBS through translational upregulation of TRPV1

OBJECTIVE: Many patients with irritable bowel syndrome IBS not only have abdominal pain but also may suffer from visceral hypersensitivity and heighted visceral nociception. Moreover, IBS has few effective therapeutic agents and mechanisms of disease are unclear. Our goals were to (i) identify micro...

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Detalhes bibliográficos
Publicado no:Gut
Main Authors: Zhou, QiQi, Yang, Liuqing, Larson, Scott, Basra, Sapreet, Merwat, Shehzad, Tan, Alai, Croce, Carlo, Verne, G Nicholas
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2016
Assuntos:
Neurogastroenterology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4853572/
https://ncbi.nlm.nih.gov/pubmed/25681400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gutjnl-2013-306464
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