Human chromosome 11 contains two different growth suppressor genes for embryonal rhabdomyosarcoma.

The identification of acquired homozygosity in human cancers implies locations of tumor suppressor genes without providing functional evidence. The localization of a defect in embryonal rhabdomyosarcomas to chromosomal region 11p15 provides one such example. In this report, we show that transfer of...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Loh, W E, Scrable, H J, Livanos, E, Arboleda, M J, Cavenee, W K, Oshimura, M, Weissman, B E
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1992
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC48531/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1347425/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.5.1755
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