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AMP-activated protein kinase mediates mitochondrial fission in response to energy stress
Mitochondria undergo fragmentation in response to electron transport chain (ETC) poisons and mitochondrial DNA–linked disease mutations, yet how these stimuli mechanistically connect to the mitochondrial fission and fusion machinery is poorly understood. We found that the energy-sensing adenosine mo...
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| Publicado no: | Science |
|---|---|
| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4852862/ https://ncbi.nlm.nih.gov/pubmed/26816379 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aab4138 |
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