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The c-rel protooncogene product c-Rel but not NF-kappa B binds to the intronic region of the human interferon-gamma gene at a site related to an interferon-stimulable response element.

Interferon-gamma (IFN-gamma) is an important immunoregulatory protein that is expressed usually only in large granular lymphocytes and T cells. The gene encoding IFN-gamma was previously found to contain an intronic enhancer element that was not tissue-specific in its activity, despite the restricte...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Sica, A, Tan, T H, Rice, N, Kretzschmar, M, Ghosh, P, Young, H A
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1992
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC48528/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1542667/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.5.1740
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