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The effects of ER morphology on synaptic structure and function in Drosophila melanogaster

Hereditary spastic paraplegia (HSP) is a set of genetic diseases caused by mutations in one of 72 genes that results in age-dependent corticospinal axon degeneration accompanied by spasticity and paralysis. Two genes implicated in HSPs encode proteins that regulate endoplasmic reticulum (ER) morphol...

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Bibliografske podrobnosti
izdano v:J Cell Sci
Main Authors: Summerville, James B., Faust, Joseph F., Fan, Ethan, Pendin, Diana, Daga, Andrea, Formella, Joseph, Stern, Michael, McNew, James A.
Format: Artigo
Jezik:Inglês
Izdano: The Company of Biologists Ltd 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4852773/
https://ncbi.nlm.nih.gov/pubmed/26906425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.184929
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