Genetic influences on schizophrenia and subcortical brain volumes: large-scale proof-of-concept and roadmap for future studies

Schizophrenia is a devastating psychiatric illness with high heritability. Brain structure and function differ, on average, between schizophrenia cases and healthy individuals. As common genetic associations are emerging for both schizophrenia and brain imaging phenotypes, we can now use genome-wide...

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Udgivet i:Nat Neurosci
Main Authors: Franke, Barbara, Stein, Jason L, Ripke, Stephan, Anttila, Verneri, Hibar, Derrek P, van Hulzen, Kimm J E, Arias-Vasquez, Alejandro, Smoller, Jordan W, Nichols, Thomas E, Neale, Michael C, McIntosh, Andrew M, Lee, Phil, McMahon, Francis J, Meyer-Lindenberg, Andreas, Mattheisen, Manuel, Andreassen, Ole A, Gruber, Oliver, Sachdev, Perminder S, Roiz-Santiañez, Roberto, Saykin, Andrew J, Ehrlich, Stefan, Mather, Karen A, Turner, Jessica A, Schwarz, Emanuel, Thalamuthu, Anbupalam, Shugart, Yin Yao, Ho, Yvonne YW, Martin, Nicholas G, Wright, Margaret J, O'Donovan, Michael C, Thompson, Paul M, Neale, Benjamin M, Medland, Sarah E, Sullivan, Patrick F
Format: Artigo
Sprog:Inglês
Udgivet: 2016
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4852730/
https://ncbi.nlm.nih.gov/pubmed/26854805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.4228
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