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Allosteric Modulation of G Protein-Coupled Receptors: An Emerging Approach of Drug Discovery

Allosteric modulation of G protein-coupled receptors (GPCRs) confers several significant advantages over the traditional targeting of orthosteric sites. While the field of allosteric modulation of GPCRs as we now know it will benefit from continued investigation, the explosion of interest has led to...

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Pubblicato in:Austin J Pharmacol Ther
Autori principali: Wild, Christopher, Cunningham, Kathryn A., Zhou, Jia
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4852709/
https://ncbi.nlm.nih.gov/pubmed/27148592
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