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Using Drosophila to discover mechanisms underlying type 2 diabetes

Mechanisms of glucose homeostasis are remarkably well conserved between the fruit fly Drosophila melanogaster and mammals. From the initial characterization of insulin signaling in the fly came the identification of downstream metabolic pathways for nutrient storage and utilization. Defects in these...

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Publicat a:Dis Model Mech
Autors principals: Alfa, Ronald W., Kim, Seung K.
Format: Artigo
Idioma:Inglês
Publicat: The Company of Biologists Ltd 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4852505/
https://ncbi.nlm.nih.gov/pubmed/27053133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.023887
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