Common arterial trunk and ventricular non-compaction in Lrp2 knockout mice indicate a crucial role of LRP2 in cardiac development

Lipoprotein-related receptor protein 2 (LRP2) is important for development of the embryonic neural crest and brain in both mice and humans. Although a role in cardiovascular development can be expected, the hearts of Lrp2 knockout (KO) mice have not yet been investigated. We studied the cardiovascul...

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Publicat a:Dis Model Mech
Autors principals: Baardman, Maria E., Zwier, Mathijs V., Wisse, Lambertus J., Gittenberger-de Groot, Adriana C., Kerstjens-Frederikse, Wilhelmina S., Hofstra, Robert M. W., Jurdzinski, Angelika, Hierck, Beerend P., Jongbloed, Monique R. M., Berger, Rolf M. F., Plösch, Torsten, DeRuiter, Marco C.
Format: Artigo
Idioma:Inglês
Publicat: The Company of Biologists Ltd 2016
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4852499/
https://ncbi.nlm.nih.gov/pubmed/26822476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.022053
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