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Retinoic acid-induced premature osteoblast-to-preosteocyte transitioning has multiple effects on calvarial development
We have previously shown that, in human and zebrafish, hypomorphic mutations of the gene encoding the retinoic acid (RA)-metabolizing enzyme Cyp26b1 result in coronal craniosynostosis, caused by an RA-induced premature transitioning of suture osteoblasts to preosteocytes, inducing ectopic mineraliza...
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| Publicado no: | Development |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Company of Biologists Ltd
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4852491/ https://ncbi.nlm.nih.gov/pubmed/26903503 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.129189 |
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