BRAF Mutation Is Associated with Improved Local Control of Melanoma Brain Metastases Treated with Gamma Knife Radiosurgery

OBJECTIVES: Evidence has implicated a possible role of tumor mutation status on local control (LC) with radiotherapy. BRAF is a proto-oncogene that is mutated in approximately 50% of patients with melanoma. We sought to analyze the influence of BRAF status on LC of melanoma brain metastases (MBM) fo...

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Bibliographische Detailangaben
Veröffentlicht in:Front Oncol
Hauptverfasser: Gallaher, Ian S., Watanabe, Yoichi, DeFor, Todd E., Dusenbery, Kathryn E., Lee, Chung K., Hunt, Matthew A., Lin, Hong-Yiou, Yuan, Jianling
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2016
Schlagworte:
Oncology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4852277/
https://ncbi.nlm.nih.gov/pubmed/27200295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2016.00107
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