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Chlamydia trachomatis growth depends on eukaryotic cholesterol esterification and is affected by Acyl-CoA:cholesterol acyltransferase inhibition
Chlamydia trachomatis is auxotrophic for a variety of essential metabolites. Inhibitors that interrupt host cell catabolism may inhibit chlamydial growth and reveal Chlamydia metabolite requirements. We used the known indoleamine-2,3-dioxygenase (IDO)-inhibitor 4-phenyl imidazole (4-PI) to reverse I...
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發表在: | Pathog Dis |
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Main Authors: | , |
格式: | Artigo |
語言: | Inglês |
出版: |
Oxford University Press
2015
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主題: | |
在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4852217/ https://ncbi.nlm.nih.gov/pubmed/25883118 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/femspd/ftv028 |
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