Role of the KIT protooncogene in normal and malignant human hematopoiesis.

The role of the KIT protooncogene in human hematopoiesis is uncertain. Therefore, we examined KIT mRNA expression in normal human bone marrow mononuclear cells (MNC) and used antisense oligodeoxynucleotides (oligomers) to disrupt KIT function. KIT mRNA was detected with certainty only in growth fact...

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Bibliographic Details
Main Authors: Ratajczak, M Z, Luger, S M, DeRiel, K, Abrahm, J, Calabretta, B, Gewirtz, A M
Format: Artigo
Language:Inglês
Published: 1992
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC48522/
https://ncbi.nlm.nih.gov/pubmed/1371882
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