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A Pot-Economical Approach to the Total Synthesis of Sch-725674

A pot-economical total synthesis of antifungal Sch-725674, 1 is reported. The approach takes advantage of a number of one-pot, sequential transformations, including a phosphate tether-mediated one-pot, sequential RCM/CM/chemoselective hydrogenation protocol, a one-pot tosylation/acrylation sequence,...

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Detalhes bibliográficos
Publicado no:Org Lett
Main Authors: Bodugam, Mahipal, Javed, Salim, Ganguly, Arghya, Torres, Jessica, Hanson, Paul R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4852165/
https://ncbi.nlm.nih.gov/pubmed/26760683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.orglett.5b03547
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