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Pulling habits out of rats: Adenosine 2A receptor antagonism in dorsomedial striatum rescues methamphetamine-induced deficits in goal-direct action

Addiction is characterised by a persistent loss of behavioural control resulting in insensitivity to negative feedback and abnormal decision-making. Here we investigated the influence of methamphetamine (METH)-paired contextual cues on decision-making in rats. Choice between goal-directed actions wa...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Addict Biol
Prif Awduron: Furlong, Teri M., Supit, Alva S. A., Corbit, Laura H., Killcross, Simon, Balleine, Bernard W.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2015
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4851927/
https://ncbi.nlm.nih.gov/pubmed/26515740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/adb.12316
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