Downregulation of p22phox in Retinal Pigment Epithelial Cells Inhibits Choroidal Neovascularization in Mice

Choroidal neovascularization (CNV) occurs in a variety of chorioretinal diseases including age-related macular degeneration (AMD), and is the major cause of severe visual loss in patients with AMD. Oxidative stress has been thought to play an important role in the development of CNV. Nicotinamide ad...

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Bibliographic Details
Published in:Mol Ther
Main Authors: Li, Qiuhong, Dinculescu, Astra, Shan, Zhiying, Miller, Rehae, Pang, Jijing, Lewin, Alfred S, Raizada, Mohan K, Hauswirth, William W
Format: Artigo
Language:Inglês
Published: 2008
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4851833/
https://ncbi.nlm.nih.gov/pubmed/18665154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2008.164
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