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A novel LAMB2 gene mutation associated with a severe phenotype in a neonate with Pierson syndrome

BACKGROUND: Pierson syndrome (PS) is a rare autosomal recessive disorder, caused by mutations in the laminin β2 (LAMB2) gene. It is characterized by congenital nephrotic syndrome, microcoria, and neurodevelopmental deficits. Several mutations with genotype–phenotype correlations have been reported,...

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Detalhes bibliográficos
Publicado no:Eur J Med Res
Main Authors: Zemrani, Boutaina, Cachat, François, Bonny, Olivier, Giannoni, Eric, Durig, Jacques, Fellmann, Florence, Chehade, Hassib
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4851796/
https://ncbi.nlm.nih.gov/pubmed/27130041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40001-016-0215-z
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