Development of a Plasmodium berghei transgenic parasite expressing the full-length Plasmodium vivax circumsporozoite VK247 protein for testing vaccine efficacy in a murine model

BACKGROUND: The approach of using transgenic rodent malaria parasites to assess the immune system’s response to antigenic targets from a human malaria parasite has been shown to be useful for preclinical evaluation of new vaccine formulations. The transgenic Plasmodium berghei parasite line [PvCSP(V...

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Bibliografske podrobnosti
izdano v:Malar J
Main Authors: Mizutani, Masanori, Fukumoto, Shinya, Soubeiga, Adam Patrice, Soga, Akira, Iyori, Mitsuhiro, Yoshida, Shigeto
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2016
Teme:
Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4851775/
https://ncbi.nlm.nih.gov/pubmed/27129682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12936-016-1297-3
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