Application of a Clinical Whole-Transcriptome Assay for Staging and Prognosis of Prostate Cancer Diagnosed in Needle Core Biopsy Specimens

Molecular and genomic analysis of microscopic quantities of tumor from formalin-fixed, paraffin-embedded biopsy specimens has many unique challenges. Herein, we evaluated the feasibility of obtaining transcriptome-wide RNA expression to measure prognostic classifiers in diagnostic prostate needle co...

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Veröffentlicht in:J Mol Diagn
Hauptverfasser: Knudsen, Beatrice S., Kim, Hyung L., Erho, Nicholas, Shin, Heesun, Alshalalfa, Mohammed, Lam, Lucia L.C., Tenggara, Imelda, Chadwich, Karen, Van Der Kwast, Theo, Fleshner, Neil, Davicioni, Elai, Carroll, Peter R., Cooperberg, Matthew R., Chan, June M., Simko, Jeffry P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Investigative Pathology 2016
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Regular Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4851733/
https://ncbi.nlm.nih.gov/pubmed/26945428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmoldx.2015.12.006
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