Preemptive Pharmacogenomic Testing for Precision Medicine: A Comprehensive Analysis of Five Actionable Pharmacogenomic Genes Using Next-Generation DNA Sequencing and a Customized CYP2D6 Genotyping Cascade

Significant barriers, such as lack of professional guidelines, specialized training for interpretation of pharmacogenomics (PGx) data, and insufficient evidence to support clinical utility, prevent preemptive PGx testing from being widely clinically implemented. The current study, as a pilot project...

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Dades bibliogràfiques
Publicat a:J Mol Diagn
Autors principals: Ji, Yuan, Skierka, Jennifer M., Blommel, Joseph H., Moore, Brenda E., VanCuyk, Douglas L., Bruflat, Jamie K., Peterson, Lisa M., Veldhuizen, Tamra L., Fadra, Numrah, Peterson, Sandra E., Lagerstedt, Susan A., Train, Laura J., Baudhuin, Linnea M., Klee, Eric W., Ferber, Matthew J., Bielinski, Suzette J., Caraballo, Pedro J., Weinshilboum, Richard M., Black, John L.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Investigative Pathology 2016
Matèries:
Regular Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4851731/
https://ncbi.nlm.nih.gov/pubmed/26947514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmoldx.2016.01.003
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