Altered kynurenine pathway metabolites in serum of chronic migraine patients

BACKGROUND: Activation of glutamate (Glu) receptors plays a key role in the pathophysiology of migraine. Both NMDA and metabotropic Glu receptors are activated or inhibited by metabolites of the kynurenine pathway, such as kynureninic acid (KYNA), quinolinic acid (QUINA), and xanthurenic acid (XA)....

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Publicado en:J Headache Pain
Autores principales: Curto, Martina, Lionetto, Luana, Negro, Andrea, Capi, Matilde, Fazio, Francesco, Giamberardino, Maria Adele, Simmaco, Maurizio, Nicoletti, Ferdinando, Martelletti, Paolo
Formato: Artigo
Lenguaje:Inglês
Publicado: Springer Milan 2016
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4851673/
https://ncbi.nlm.nih.gov/pubmed/27130315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s10194-016-0638-5
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