Distinct Roles of Type I and Type III Interferons in Intestinal Immunity to Homologous and Heterologous Rotavirus Infections

Type I (IFN-α/β) and type III (IFN-λ) interferons (IFNs) exert shared antiviral activities through distinct receptors. However, their relative importance for antiviral protection of different organ systems against specific viruses remains to be fully explored. We used mouse strains deficient in type...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Lin, Jian-Da, Feng, Ningguo, Sen, Adrish, Balan, Murugabaskar, Tseng, Hsiang-Chi, McElrath, Constance, Smirnov, Sergey V., Peng, Jianya, Yasukawa, Linda L., Durbin, Russell K., Durbin, Joan E., Greenberg, Harry B., Kotenko, Sergei V.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4851417/
https://ncbi.nlm.nih.gov/pubmed/27128797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005600
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