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Quorum-Sensing Synchronization of Synthetic Toggle Switches: A Design Based on Monotone Dynamical Systems Theory

Synthetic constructs in biotechnology, biocomputing, and modern gene therapy interventions are often based on plasmids or transfected circuits which implement some form of “on-off” switch. For example, the expression of a protein used for therapeutic purposes might be triggered by the recognition of...

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Détails bibliographiques
Publié dans:PLoS Comput Biol
Auteurs principaux: Nikolaev, Evgeni V., Sontag, Eduardo D.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4851387/
https://ncbi.nlm.nih.gov/pubmed/27128344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1004881
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