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Dendrimers Target the Ischemic Lesion in Rodent and Primate Models of Nonarteritic Anterior Ischemic Optic Neuropathy

INTRODUCTION: Polyamidoamine dendrimer nanoparticles (~ 4 nanometers) are inert polymers that can be linked to biologically active compounds. These dendrimers selectively target and accumulate in inflammatory cells upon systemic administration. Dendrimer-linked compounds enable sustained release of...

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Publicado en:PLoS One
Main Authors: Guo, Yan, Johnson, Mary A., Mehrabian, Zara, Mishra, Manoj K., Kannan, Rangaramanujam, Miller, Neil R., Bernstein, Steven L.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4851377/
https://ncbi.nlm.nih.gov/pubmed/27128315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0154437
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