Candidalysin is a fungal peptide toxin critical for mucosal infection

Cytolytic proteins and peptide toxins are classical virulence factors of several bacterial pathogens which disrupt epithelial barrier function, damage cells and activate or modulate host immune responses. Until now human pathogenic fungi were not known to possess such toxins. Here we identify the fi...

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Detaylı Bibliyografya
Yayımlandı:Nature
Asıl Yazarlar: Moyes, David L., Wilson, Duncan, Richardson, Jonathan P., Mogavero, Selene, Tang, Shirley X., Wernecke, Julia, Höfs, Sarah, Gratacap, Remi L., Robbins, Jon, Runglall, Manohursingh, Murciano, Celia, Blagojevic, Mariana, Thavaraj, Selvam, Förster, Toni M., Hebecker, Betty, Kasper, Lydia, Vizcay, Gema, Iancu, Simona I., Kichik, Nessim, Häder, Antje, Kurzai, Oliver, Luo, Ting, Krüger, Thomas, Kniemeyer, Olaf, Cota, Ernesto, Bader, Oliver, Wheeler, Robert T., Gutsmann, Thomas, Hube, Bernhard, Naglik, Julian R.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2016
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4851236/
https://ncbi.nlm.nih.gov/pubmed/27027296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature17625
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