Validation of the FAM19A4/mir124-2 DNA methylation test for both lavage- and brush-based self-samples to detect cervical (pre)cancer in HPV-positive women

OBJECTIVES: DNA methylation analysis of cancer-related genes is a promising tool for HPV-positive women to identify those with cervical (pre)cancer (CIN3+) in need of treatment. However, clinical performance of methylation markers can be influenced by the sample type utilized. We describe a multiple...

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Publicado no:Gynecol Oncol
Main Authors: De Strooper, Lise M.A., Verhoef, Viola M.J., Berkhof, Johannes, Hesselink, Albertus T., de Bruin, Helena M.E., van Kemenade, Folkert J., Bosgraaf, Remko P., Bekkers, Ruud L.M., Massuger, Leon F.A.G., Melchers, Willem J.G., Steenbergen, Renske D.M., Snijders, Peter J.F., Meijer, Chris J.L.M., Heideman, Daniëlle A.M.
Formato: Artigo
Idioma:Inglês
Publicado em: Academic Press 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4851217/
https://ncbi.nlm.nih.gov/pubmed/26921784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ygyno.2016.02.012
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