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Biology of CML stem cells: the basis for clinical heterogeneity?

Although chronic myeloid leukemia (CML) is now defined on the basis of the presence of the BCR-ABL1 fusion gene, which may or may not be the initial genetic event that triggers the inappropriate expansion of the myeloid cell mass, CML, similar to other leukemias, is in fact clinically heterogeneous....

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Detalhes bibliográficos
Publicado no:Leukemia Suppl
Main Authors: Goldman, J M, Gordon, M, Bazeos, A, Marin, D
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4851204/
https://ncbi.nlm.nih.gov/pubmed/27175247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leusup.2012.23
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