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Differential methylation at the RELN gene promoter in temporal cortex from autistic and typically developing post-puberal subjects
BACKGROUND: Reelin plays a pivotal role in neurodevelopment and in post-natal synaptic plasticity and has been implicated in the pathogenesis of autism spectrum disorder (ASD). The reelin (RELN) gene expression is significantly decreased in ASD, both in the brain and peripherally. Methylation at the...
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| Publicado no: | J Neurodev Disord |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4850686/ https://ncbi.nlm.nih.gov/pubmed/27134686 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s11689-016-9151-z |
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