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PATZ1 is a target of miR-29b that is induced by Ha-Ras oncogene in rat thyroid cells

The regulatory transcriptional factor PATZ1 is constantly downregulated in human thyroid cancer where it acts as a tumour suppressor by targeting p53-dependent genes involved in Epithelial-Mesenchymal Transition and cell migration. The aim of the present work was to elucidate the upstream signalling...

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Publicat a:Sci Rep
Autors principals: Vitiello, Michela, Valentino, Teresa, De Menna, Marta, Crescenzi, Elvira, Francesca, Paola, Rea, Domenica, Arra, Claudio, Fusco, Alfredo, De Vita, Gabriella, Cerchia, Laura, Fedele, Monica
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4850481/
https://ncbi.nlm.nih.gov/pubmed/27125250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep25268
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