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Signal Transduction Pathways of EMT Induced by TGF-β, SHH, and WNT and Their Crosstalks

Epithelial-to-mesenchymal transition (EMT) is a key step in development, wound healing, and cancer development. It involves cooperation of signaling pathways, such as transformation growth factor-β (TGF-β), Sonic Hedgehog (SHH), and WNT pathways. These signaling pathways crosstalk to each other and...

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Detalhes bibliográficos
Publicado no:J Clin Med
Main Authors: Zhang, Jingyu, Tian, Xiao-Jun, Xing, Jianhua
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4850464/
https://ncbi.nlm.nih.gov/pubmed/27043642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jcm5040041
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