Regulation of Cl- channels in normal and cystic fibrosis airway epithelial cells by extracellular ATP.
The rate of Cl- secretion by human airway epithelium is determined, in part, by apical cell membrane Cl- conductance. In cystic fibrosis airway epithelia, defective regulation of Cl- conductance decreases the capability to secrete Cl-. Here we report that extracytosolic ATP in the luminal bath of cu...
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| Publicat a: | Proc Natl Acad Sci U S A |
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| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
1992
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC48504/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1371880/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.5.1621 |
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