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Disulfide Bridges: Bringing Together Frustrated Structure in a Bioactive Peptide

Disulfide bridges are commonly found covalent bonds that are usually believed to maintain structural stability of proteins. Here, we investigate the influence of disulfide bridges on protein dynamics through molecular dynamics simulations on the cysteine-rich trypsin inhibitor MCoTI-II with three di...

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Detalhes bibliográficos
Publicado no:Biophys J
Main Authors: Zhang, Yi, Schulten, Klaus, Gruebele, Martin, Bansal, Paramjit S., Wilson, David, Daly, Norelle L.
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4850350/
https://ncbi.nlm.nih.gov/pubmed/27119635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2016.03.027
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