O-Glycosylation of a Secretory Granule Membrane Enzyme Is Essential for Its Endocytic Trafficking

Peptidylglycine α-amidating monooxygenase (PAM) (EC 1.14.17.3) catalyzes peptide amidation, a crucial post-translational modification, through the sequential actions of its monooxygenase (peptidylglycine α-hydroxylating monooxygenase) and lyase (peptidyl-α-hydroxyglycine α-amidating lyase (PAL)) dom...

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Bibliografiska uppgifter
I publikationen:J Biol Chem
Huvudupphovsmän: Vishwanatha, Kurutihalli S., Bäck, Nils, Lam, TuKiet T., Mains, Richard E., Eipper, Betty A.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Biochemistry and Molecular Biology 2016
Ämnen:
Cell Biology
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4850319/
https://ncbi.nlm.nih.gov/pubmed/26961877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.711838
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