Characterization of an inversion on the long arm of chromosome 10 juxtaposing D10S170 and RET and creating the oncogenic sequence RET/PTC.

RET/PTC is a transforming sequence created by the fusion of the tyrosine kinase domain of the RET protooncogene with the 5' end of the locus D10S170 designated by probe H4 and is frequently found activated in human papillary thyroid carcinomas. RET and D10S170 have been mapped to contiguous regions...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Pierotti, M A, Santoro, M, Jenkins, R B, Sozzi, G, Bongarzone, I, Grieco, M, Monzini, N, Miozzo, M, Herrmann, M A, Fusco, A
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1992
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC48503/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1542652/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.5.1616
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