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Identification of Unintuitive Features of Sumoylation through Mathematical Modeling
Sumoylation is a multistep, multienzymatic post-translational modification in which a small ubiquitin-like modifier protein (SUMO) is attached to the target. We present the first mathematical model for sumoylation including enzyme mechanism details such as autosumoylation of E2 and multifunctional n...
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Publicado no: | J Biol Chem |
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Main Authors: | , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society for Biochemistry and Molecular Biology
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4850286/ https://ncbi.nlm.nih.gov/pubmed/26861881 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.676122 |
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