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Identification of Unintuitive Features of Sumoylation through Mathematical Modeling

Sumoylation is a multistep, multienzymatic post-translational modification in which a small ubiquitin-like modifier protein (SUMO) is attached to the target. We present the first mathematical model for sumoylation including enzyme mechanism details such as autosumoylation of E2 and multifunctional n...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Puntambekar, Shraddha S., Nyayanit, Dimpal, Saxena, Priyanka, Gadgil, Chetan J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4850286/
https://ncbi.nlm.nih.gov/pubmed/26861881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.676122
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