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TRIP6 antagonizes the recruitment of A20 and CYLD to TRAF6 to promote the LPA2 receptor-mediated TRAF6 activation
The elevated lysophosphatidic acid signaling has been causally linked to cancer-associated inflammation and tumorigenesis through upregulation of nuclear factor-κB signaling. However, how this signaling event is regulated has not yet been fully understood. Here we demonstrate that TRIP6, an LPA2 rec...
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Publicat a: | Cell Discov |
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Autors principals: | , , , |
Format: | Artigo |
Idioma: | Inglês |
Publicat: |
Nature Publishing Group
2016
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Matèries: | |
Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4850058/ https://ncbi.nlm.nih.gov/pubmed/27134758 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/celldisc.2015.48 |
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