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TRIP6 antagonizes the recruitment of A20 and CYLD to TRAF6 to promote the LPA2 receptor-mediated TRAF6 activation

The elevated lysophosphatidic acid signaling has been causally linked to cancer-associated inflammation and tumorigenesis through upregulation of nuclear factor-κB signaling. However, how this signaling event is regulated has not yet been fully understood. Here we demonstrate that TRIP6, an LPA2 rec...

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Publicat a:Cell Discov
Autors principals: Lin, Fang-Tsyr, Lin, Vivian Y, Lin, Victor T G, Lin, Weei-Chin
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2016
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4850058/
https://ncbi.nlm.nih.gov/pubmed/27134758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/celldisc.2015.48
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