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Voltage gated sodium channels as drug discovery targets

Voltage-gated sodium (Na(V)) channels are a family of transmembrane ion channel proteins. They function by forming a gated, water-filled pore to help establish and control cell membrane potential via control of the flow of ions between the intracellular and the extracellular environments. Blockade o...

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Detalles Bibliográficos
Publicado en:Channels (Austin)
Autores principales: Bagal, Sharan K, Marron, Brian E, Owen, Robert M, Storer, R Ian, Swain, Nigel A
Formato: Artigo
Lenguaje:Inglês
Publicado: Taylor & Francis Group, LLC 2015
Materias:
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4850042/
https://ncbi.nlm.nih.gov/pubmed/26646477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19336950.2015.1079674
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