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Whole-Body and Microenvironmental Localization of Radium-223 in Naïve and Mouse Models of Prostate Cancer Metastasis

BACKGROUND: Bone-metastatic, castration-resistant prostate cancer (bmCRPC) represents a lethal stage of the most common noncutaneous cancer in men. The recent introduction of Radium-223 dichloride, a bone-seeking alpha particle (α)–emitting radiopharmaceutical, demonstrates statistically significant...

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Publicat a:J Natl Cancer Inst
Autors principals: Abou, Diane S., Ulmert, David, Doucet, Michele, Hobbs, Robert F., Riddle, Ryan C., Thorek, Daniel L. J.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4849807/
https://ncbi.nlm.nih.gov/pubmed/26683407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnci/djv380
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