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Circulating fibrocytes traffic to the lungs in response to CXCL12 and mediate fibrosis

Previous reports have identified a circulating pool of CD45(+) collagen I(+) CXCR4(+) (CD45(+)Col I(+)CXCR4(+)) cells, termed fibrocytes, that traffic to areas of fibrosis. No studies have demonstrated that these cells actually contribute to fibrosis, however. Pulmonary fibrosis was originally thoug...

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Main Authors: Phillips, Roderick J., Burdick, Marie D., Hong, Kurt, Lutz, Marin A., Murray, Lynne A., Xue, Ying Ying, Belperio, John A., Keane, Michael P., Strieter, Robert M.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Clinical Investigation 2004
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC484979/
https://ncbi.nlm.nih.gov/pubmed/15286810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200420997
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