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Bovine Leukemia Virus Small Noncoding RNAs Are Functional Elements That Regulate Replication and Contribute to Oncogenesis In Vivo

Retroviruses are not expected to encode miRNAs because of the potential problem of self-cleavage of their genomic RNAs. This assumption has recently been challenged by experiments showing that bovine leukemia virus (BLV) encodes miRNAs from intragenomic Pol III promoters. The BLV miRNAs are abundant...

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發表在:PLoS Pathog
Main Authors: Gillet, Nicolas A., Hamaidia, Malik, de Brogniez, Alix, Gutiérrez, Gerónimo, Renotte, Nathalie, Reichert, Michal, Trono, Karina, Willems, Luc
格式: Artigo
語言:Inglês
出版: Public Library of Science 2016
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4849745/
https://ncbi.nlm.nih.gov/pubmed/27123579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005588
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