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MicroRNA Seed Region Length Impact on Target Messenger RNA Expression and Survival in Colorectal Cancer

microRNAs (miRNA) repress messenger RNAs post-transcriptionally through binding to the 3’ UTR of the mRNA with the miRNA seed region. It has been purported that longer seed regions have a greater efficacy on mRNA repression. We tested this hypothesis by evaluating differential expression of miRNAs i...

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Bibliografiske detaljer
Udgivet i:PLoS One
Main Authors: Mullany, Lila E., Herrick, Jennifer S., Wolff, Roger K., Slattery, Martha L.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4849741/
https://ncbi.nlm.nih.gov/pubmed/27123865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0154177
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