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Chronic restraint stress triggers the dopaminergic and noradrenergic neurodegeneration: possible role of chronic stress for the onset of Parkinson’s disease

Parkinson’s disease (PD) is a neurodegenerative disease characterized by the loss of dopaminergic (DA) neurons in the substantia nigra pars compacta (SNpc) and, to a lesser extent, in the noradrenergic neurons of the locus coeruleus (LC). Most cases of PD are idiopathic and sporadic and are believed...

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Detalhes bibliográficos
Publicado no:Brain Behav Immun
Main Authors: Sugama, Shuei, Sekiyama, Kazunari, Kodama, Tohru, Takamatsu, Yoshiki, Takenouchi, Takato, Hashimoto, Makoto, Bruno, Conti, Kakinuma, Yoshihiko
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4849407/
https://ncbi.nlm.nih.gov/pubmed/26291405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbi.2015.08.015
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