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Modulation of hepcidin to treat iron deregulation: potential clinical applications
The secreted peptide hormone hepcidin regulates systemic and local iron homeostasis through degradation of the iron exporter ferroportin. Dysregulation of hepcidin leads to altered iron homeostasis and development of pathological disorders including hemochromatosis, and iron loading and iron restric...
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| Veröffentlicht in: | Expert Rev Hematol |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4849272/ https://ncbi.nlm.nih.gov/pubmed/26669208 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1586/17474086.2016.1124757 |
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