Bone Marrow–derived Cells Contribute to the Pathogenesis of Pulmonary Arterial Hypertension

Rationale: Pulmonary arterial hypertension (PAH) is a progressive lung disease of the pulmonary microvasculature. Studies suggest that bone marrow (BM)-derived circulating cells may play an important role in its pathogenesis. Objectives: We used a genetic model of PAH, the Bmpr2 mutant mouse, to stu...

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Bibliographic Details
Published in:Am J Respir Crit Care Med
Main Authors: Yan, Ling, Chen, Xinping, Talati, Megha, Nunley, Bethany Womack, Gladson, Santhi, Blackwell, Tom, Cogan, Joy, Austin, Eric, Wheeler, Ferrin, Loyd, James, West, James, Hamid, Rizwan
Format: Artigo
Language:Inglês
Published: American Thoracic Society 2016
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4849178/
https://ncbi.nlm.nih.gov/pubmed/26651104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201502-0407OC
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