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Attenuation of the programmed cell death-1 pathway increases the M1 polarization of macrophages induced by zymosan

Programmed cell death-1 (PD-1) is a member of the CD28 superfamily that delivers negative signals on interaction with its 2 ligands, PD-L1 and PD-L2. We assessed the contribution of the PD-1 pathway to regulating the polarization of macrophages that promote inflammation induced by zymosan. We found...

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Vydáno v:Cell Death Dis
Hlavní autoři: Chen, W, Wang, J, Jia, L, Liu, J, Tian, Y
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4849159/
https://ncbi.nlm.nih.gov/pubmed/26913605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2016.33
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