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Activator-inhibitor coupling between Rho signaling and actin assembly make the cell cortex an excitable medium

Animal cell cytokinesis results from patterned activation of the small GTPase Rho, which directs assembly of actomyosin in the equatorial cortex. Cytokinesis is restricted to a portion of the cell cycle following anaphase onset in which the cortex is responsive to signals from the spindle. We show t...

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Foilsithe in:Nat Cell Biol
Main Authors: Bement, William M., Leda, Marcin, Moe, Alison M., Kita, Angela M., Larson, Matthew E., Golding, Adriana E., Pfeuti, Courtney, Su, Kuan-Chung, Miller, Ann L., Goryachev, Andrew B., von Dassow, George
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2015
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4849138/
https://ncbi.nlm.nih.gov/pubmed/26479320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb3251
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