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Design of a randomized controlled trial of extended-release naltrexone versus daily buprenorphine-naloxone for opioid dependence in Norway (NTX-SBX)

BACKGROUND: Current guidelines for opioid dependence recommend daily maintenance of physical dependence with methadone or buprenorphine, and discourage abstinence due to the high risk of relapse and overdose. Extended-release formulations of the opioid antagonist naltrexone (XR-NTX) block heroin and...

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Publicat a:BMC Pharmacol Toxicol
Autors principals: Kunøe, Nikolaj, Opheim, Arild, Solli, Kristin Klemmetsby, Gaulen, Zhanna, Sharma-Haase, Kamni, Latif, Zill-e-Huma, Tanum, Lars
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4848871/
https://ncbi.nlm.nih.gov/pubmed/27121539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40360-016-0061-1
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