Rhus verniciflua Stokes (RVS) and butein induce apoptosis of paclitaxel-resistant SKOV-3/PAX ovarian cancer cells through inhibition of AKT phosphorylation

BACKGROUND: Rhus verniciflua Stokes (RVS) belongs to the Anacardiaceae family and traditionally used for cancer treatment. RVS and butein, a major compound of RVS, were known to induce apoptosis via AKT inhibition in cancer cells. Thus, in this study, we investigated the effect of RVS and its deriva...

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Bibliographic Details
Published in:BMC Complement Altern Med
Main Authors: Choi, Hyeong Sim, Kim, Min Kyoung, Choi, Youn Kyung, Shin, Yong Cheol, Cho, Sung-Gook, Ko, Seong-Gyu
Format: Artigo
Language:Inglês
Published: BioMed Central 2016
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4848824/
https://ncbi.nlm.nih.gov/pubmed/27121110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12906-016-1103-3
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